Urticaria is an interdisciplinary problem and also appears in the oncologist’s practice. Reports of the literature shows that cancer may be associated with malignant disease as a revelator, the symptom, as well as be the result of long and often burdened with diverse oncological toxicity therapy. Urticaria, much more often, seems to be a consequence of oncological treatment irrespective of the fact of dealing with chemotherapy, radiation therapy or adjunctive treatment of malignant disease than its revelator. As the cancer revelator it often has a chronic condition, opposite to that found in caner therapy. Pathomechanism of urticaria, as indeed of other allergic diseases, in cases concerning the situation of cancer is not known.