Is it possible to eradicate Psuedomonas aeruginosa in cystic fibrosis children?
Opracowanie grupy roboczej Red Point pod kierunkiem dr. n. med. Marka Popielarza w ramach projektu „Trudne pytania w pulmonologii dziecięcej”.
Współautorzy: Aleksandrowicz I., Balicka V., Górnicka G., Grabowski M., Janicki K.,
Kowalska M., Kuźmińska U., Sypniewska-Ciesielska A., Stanisz J., Szołtysek H.
Cystic fibrosis (CF) is a worldwide human genetic disease affecting the exocrine (mucus) glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure. CF is caused by a mutation in the gene, cystic fibrosis transmembrane conductance regulator (CFTR). The lungs of individuals with cystic fibrosis are colonized and infected by Pseudomonas aeruginosa. The lungs respond to repeated damage by thick secretions and chronic infections by gradually remodeling the lower airways.
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