The cell composition of infiltration of gastric mucosa in patients with food allergy
Małgorzata Graczyk, Andrzej Kuźmiński, Michał Przybyszewski, Magdalena Żbikowska-Gotz, Alicja Sławińska, Zbigniew Bartuzi
Katedra i Klinika Alergologii, Immunologii Klinicznej i Chorób Wewnętrznych Collegium Medicum w Bydgoszczy, Uniwersytet Mikołaja Kopernika w Toruniu
Introduction: To examine the cell composition of infiltration of gastric mucosa in patients with food allergy.
Material and methods: The research was carried out in 80 patients: 50 with the food allergy and 30 with symptoms of gastric dyspepsy without the food allergy. Every patient had gastrooesophagoduodenoscopy, histopathological examination of specimens of the mucous membrane of the stomach with the estimation of presence of eosinophil cells in gastric inflammatory infiltration and presence of the Helicobacter pylori colonization.
Results: The presence of eosinophil cells for histopathological examination of specimens of the mucous membrane of the stomach in patient with food allergy was shown at 42% of examined patients, but the number above 10 in the field of view was shown at 20% of patients. However in the group without allergy the presence of eosinophil cells was shown at 30%, and eosinophil cell infiltration above 10 in the field of view was shown only at 6,67% of examined patients. The Helicobacter pylori colonization among patients with food allergy was shown at 38% of examined patients, and at 60% of patients with gastric dyspepsy without the food allergy.
Conclusions: In our study we shown, that the presence of eosinophil cells at histopathological examination of specimens of the mucous membrane of the stomach was higher among patients with food allergy in the comparison with patients without food allergy, but the differences were not significant.
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